Alnylam Pharmaceuticals
ABOUT ALNYLAM
Our Science Is Changing the Way Medicine Treats DiseaseTM
Alnylam has led the translation of RNAi (RNA interference) from Nobel Prize-winning discovery into an innovative, entirely new class of medicines. Founded in 2002 by a team of distinguished life sciences leaders, Alnylam’s vision is to harness the potential of RNAi therapeutics to transform the lives of people living with diseases for which there are limited or inadequate treatment options. Our pioneering work has delivered the world’s first and only approved RNAi therapeutics—ONPATTRO® (patisiran) in 2018, GIVLAARI® (givosiran) in 2019, OXLUMO® (lumasiran) in 2020, and AMVUTTRA® (vutrisiran) in 2022. We are advancing a deep pipeline of innovative RNAi-based medicines in four therapeutic areas: genetic medicines, cardio-metabolic diseases, infectious diseases, and central nervous system (CNS) and ocular diseases.

What’s in a Name?
AL-NY-LAM. Our name may not be the easiest to pronounce, but once you learn it, you’ll never forget it. Alnylam is derived from “Alnilam,” the bright center star in the constellation Orion’s belt, which has been used by navigators for thousands of years and symbolizes our passion for discovery.
RNAi Therapeutics—An Innovative New Class of Medicines
Medicines based on RNAi work by “silencing” or disabling the production (“expression”) of the genes that cause specific diseases. In doing so, RNAi therapeutics work “upstream” of most other classes of medicines, such as small molecules and monoclonal antibodies, by targeting the “root” genetic cause of a disease rather than its symptoms. To learn more about our science, click here.
RNAi is the core discovery that forms the therapies Alnylam is developing. It is recognized as a major scientific breakthrough—but how does it work, exactly?

Vision, Mission, and Values
Our Vision - Harnessing a revolution in biology for human health®.
Our Mission - Build a top-tier, global, independent biopharmaceutical company founded on RNAi.
Our Core Values - Commitment to People, Innovation & Discovery, Sense of Urgency, Open Culture, and Passion for Excellence.
CAREERS AT ALNYLAM
Join Our Team and Grow With Us
At Alnylam, we are driven by our mission to translate the Nobel Prize-winning discovery of RNA interference (RNAi) into an innovative, new class of medicines. We’re motivated in this endeavor by the bravery and perseverance of people with unmet medical needs who live with rare and genetic diseases. They are the focus of our efforts, and we exist as a company because of them. That knowledge and commitment to patients is present in everything we do, every day.

At The Forefront of What’s Next
For Patients
Our goal, which is well underway, is to become a world-class biopharmaceutical company that can independently develop and deliver innovative medicines based on RNAi to patients worldwide. We have a deep pipeline of early to late stage investigational therapies, and 2018 marked the approval of our first medicine—the world’s first RNAi therapeutic. Even though we’ve been around since 2002, we’re just getting started!
For Employees
We are growing quickly and hiring across North America, Europe, Asia, and Latin America for a wide variety of roles. We’re seeking smart, passionate, “change the world” kind of people who are ready to say, “challenge accepted.” Our 1,500 (and counting!) employees are building a diverse, equitable, inclusive, and high-performing global organization that celebrates team achievement and recognizes individual contributions.
We’re at the forefront of what’s next for patients, and perhaps your career also.
Search among Alnylam Pharmaceuticals jobs
| Jobs: 11 - 20 of 98 |
Senior Manager, GCP Process Excellence
Cambridge, Massachusetts
Overview Reporting to the Associate Director of Standards, Process & Training - Clinical Development, the Sr Manager, GCP Process Managementserves as a process excellence Subject Matter Expert (SME) on process improvement, management and ef...
2d
| Job Type | Full Time |
Cambridge, Massachusetts
Overview The VP, Head of US TTR Marketing, is a highly visible, mission-critical role that will report to the SVP, US Head of Business and will be a core member of the US Leadership Team. This person will be pivotal in defining the goals, s...
2d
| Job Type | Full Time |
Supervisor, Manufacturing-Second Shift
Cambridge, Massachusetts
Overview The Supervisor, Manufacturing provides direct and detailed GMP manufacturing oversight of clinical drug substance manufacturing at Alnylam's Norton manufacturing site. The Supervisor is responsible for management of Manufacturing t...
2d
| Job Type | Full Time |
Senior Manager, Clinical Quality Site Oversight (R&D QA)
Cambridge, Massachusetts
Overview The Clinical Site Quality Oversight Lead supports the execution of quality oversight activities designed to monitor and drive improvements in clinical investigator site quality performance across programs. This position works close...
2d
| Job Type | Full Time |
Director, Global Trade Compliance and Strategy
Cambridge, Massachusetts
Overview The Director, Head of Global Trade Compliance and Strategy is a key supply chain leader responsible for designing, implementing, and overseeing the company's global trade compliance program while shaping trade-related strategy to s...
3d
| Job Type | Full Time |
Cambridge, Massachusetts
Overview: Alnylam is seeking an Employment Counsel to provide strategic leadership for the Company's global employment law function. Reporting to the SVP, General Counsel, Corporate and Governance, this role will evolve, lead and execute Al...
3d
| Job Type | Full Time |
Senior Manager, Global Strategic Sourcing
Cambridge, Massachusetts
Role Overview The Senior Manager, Global Indirect Strategic Sourcing is responsible for leading and optimizing external spend across key G&A and Commercial category families. This role will own select subcategories within areas such as IT, ...
4d
| Job Type | Full Time |
Executive Director, Head of Search & Evaluation, Business Development
Cambridge, Massachusetts
Overview For the Executive Director, Head of Search & Evaluation role, we are seeking an experienced business development (BD) leader with deep scientific expertise and passion for innovation to source and evaluate external innovation and b...
4d
| Job Type | Full Time |
Associate Scientist II, Conjugation Chemistry
Cambridge, Massachusetts
Overview We are seeking an associate scientist-II to join our protein sciences team to contribute to our protein production and conjugation efforts. The candidate must be independent, goal oriented, technically competent, and able to effici...
4d
| Job Type | Full Time |
Senior Manager, Clinical Trial Disclosure and Transparency
Cambridge, Massachusetts
The Senior Manager, Clinical Trial Disclosure and Transparency is a key member of the Clinical Trial Disclosure and Transparency (CTDT) team working within the Alnylam Medical Writing Expertise Area. The Senior Manager, CTDT is responsible ...
4d
| Job Type | Full Time |