Research / Sr. Research Expert, Tumor Biology

Incyte is a fast-growing biopharmaceutical company focused on the discovery, development, and commercialization of novel medicines to meet serious unmet medical needs in oncology, inflammation and autoimmunity. Incyte is committed to the rigorous pursuit of research and development excellence to improve the lives of patients, make a difference in health care, and build sustainable value.

Incyte is proud to be recognized as a top employer by Science and seeks to create an environment where innovation, collaboration and respect for each other are prioritized. Incyte is guided by its mission to Solve On. for patients around the world - it is a workplace where problems get solved and lives are transformed. Located in Wilmington, DE, Incyte employees enjoy a rewarding and dynamic environment, competitive compensation, an affordable cost of living and proximity to leading academic and medical institutions in Philadelphia, Baltimore, New York and Washington D.C.

Our tumor biology group is looking for an experienced scientist whose key responsibilities will be to

• Independently design, execute and interpret in vitro pharmacology experiments to guide compound SAR development and explore therapeutic potential of drug targets
• Apply chemical and genetic tools as well as state-of-art technologies to interrogate cancer biology and understand the mechanism of actions of novel targets
• Identify or develop appropriate in vitro model systems to answer key biological or pharmacological questions
• Familiar with small molecule screening initiatives for exploratory and lead optimization programs.
• Work collaboratively across multiple functional groups to achieve drug discovery goals
• Evaluate data, prepare reports and presentations for internal and external meetings
• Ability to work independently and collaboratively, with strong organizational, verbal, and written communication skills.

Qualifications (Minimal acceptable level of education, work experience, and competency)

• BS/MS in Pharmacology, Molecular, Cellular or Cancer Biology or related field
• Preferred industry experience in the pharmaceutical or biotech industry
• Strong background in cancer biology and comprehensive knowledge of oncogenic signaling pathways
• Expertise in developing high throughput/scalable in vitro assays to investigate multiple cellular processes.
• Experience in advanced cell culture techniques, including three-dimensional (3-D) cell culture systems, co-culture systems and organoid culture systems
• Hands-on experience in cell culture and cell-based assays for compound screening using platforms such as ELISA, HTRF, MSD, and CTG.
• Proven experience in general molecular biology techniques (western blot, qPCR, flow cytometry etc.)
• Strong communication skills; publication record or equivalent demonstration of scientific contribution is valued
• Ability to thrive in a collaborative and evolving environment.

Disclaimer: The above statements are intended to describe the general nature and level of work performed by employees assigned to this job. They are not intended to be an exhaustive list of all duties, responsibilities, and qualifications. Management reserves the right to change or modify such duties as required.

Incyte Corporation is committed to creating a diverse environment and is proud to be an equal opportunity employer.

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